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Microglia respond to local and systemic inflammatory stimuli by producing pro-inflammatory cytokines (PIC), including interleukin-1 and (IL-1 and IL-1), tumor necrosis factor (TNF-), and interleukin-6 (IL-6) (79)

It helps to protect cells from free radical damage, neutralizes toxins, and aids in the production of other antioxidants like vitamins C and E

its predictive value requires validation in large cohorts that account for multidrug exposures and the context of immunotherapy

To elucidate the mechanism behind the beneficial effects of glutathione, further studies that examine the incorporation of orally administrated glutathione into the liver and the effects on the host redox system using stable isotope-labeled glutathione and animal models are required