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In summary, niacin is essential to the biochemistry of the nervous system, contributing to energy metabolism, neurotransmitter synthesis, such as serotonin and dopamine, antioxidant activities, and DNA repair (56)

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Acute brain refueling [62] can be from the peripheral source (counteracted insulin seizures [62]) and the recovered activity in previously hypoglycemia-silenced brain regions such as the cortex, hippocampus, and amygdala [270]