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The engagement of multiple PD-relevant mechanisms is consistent with the reported pleiotropic activity of CO, which binds with high affinity to heme-containing proteins in the body and the brain 50

Steinberger E, Kollmeier M, McBride S, Novak C, Pei X, Zelefsky MJ

Rather than remove the smoke particles, though, ozone treatment works to chemically change the structure of the smoke molecules in order to eliminate the smell