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Key contributing factors include limited access to the HBV vaccine in certain countries, noncompliance with multi-dose regimens, and the presence of vaccine non-responders, estimated at 16% of the population, which are more prevalent among older individuals, those with obesity, and smokers 8,9,10,11

Not all of them are at the undetectable level, but a lot of them do have really low or almost undetectable levels of carcinogens that we look for in tobacco products, even though most pouches do get their nicotine from tobacco