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Athough annotated plant GPXs use TRXs more efficiently than GSH, at least two other types of enzyme could be important in peroxidation of glutathione (Figure 6)

However, it needs to be stated that the US patient case was non-compliant to medical therapy

These findings suggest that UroA may have broad applications for improving energy metabolism, especially in populations experiencing age-related declines in mitochondrial efficiency (Reference Andreux, Blanco-Bose and Ryu14)