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In vitro barrier models using Caco-2 cells (gut epithelium) or brain endothelial cells could be employed to test the hypothesis that microbiota metabolites, such as butyrateeither administered directly or derived from patient-derived fecal microbiota culturescan strengthen epithelial and endothelial barrier function and reduce oxidative stress [40]

An inspection of the facility also revealed failures to establish specifications and processes for testing and documentation of the contents of the supplements

As a cofactor for enzymatic reactions, it participates in DNA synthesis and repair, part of cellular maintenance