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To clarify how integrated safety data operates in practice, the following areas are addressed: Clinical safety monitoring during development Pharmacovigilance Adverse Event Assessment Post-approval safety oversight and signal detection Regulatory documentation and data traceability Clinical Safety Monitoring During Drug Development Clinical teams monitor safety data continuously during trials to detect emerging risks early

Upon reaching the tumor, FeS@SRB release Fe 2+ in the weakly acidic tumor microenvironment to trigger Fenton reaction, generating highly oxidative hydroxyl radicals (OH) to destroy tumor cells

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