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This interplay highlights that dysregulated PCD is likely a key contributor to the pathogenesis of DOR, rather than a singular causative factor

A significant amount of research has indicated that individuals with anaemia frequently experience osteoporosis as well (125, 126), which may be related to iron overload-mediated ferroptosis caused by long-term blood transfusions in anaemia patients (127), and their fracture risk is associated with the frequency of blood transfusions (128)

66 Poor sleep may have similar bidirectional relationships with other causes of dementia, including poor cerebrovascular health

Higher hyodeoxycholic acid and certain ratios were associated with lower CSF A142