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Dynamic catalysis of metal nanozymes With the integration of energy science and materials science, the design of nanozymes has gradually expanded from static catalysis to energy-driven synergistic catalysis systems

Targeting of splice variants of human cytochrome P450 2C8 (CYP2C8) to mitochondria and their role in arachidonic acid metabolism and respiratory dysfunction

Transport-exclusion pharmacology to localize lactate dehydrogenase activity within cells

The key principle is that any combination therapy should be initiated and monitored under close medical supervision, with dose adjustments made based on glucose monitoring results and individual patient response